Evaluation of the ability of an organic derivative of ruthenium(II) to reinforce the cytotoxicity of fast neutron against malignant cells in culture
(2008) Letters in Drug Design & Discovery — Vol. 5, n° 1, p. 1-6 (2008)
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- Abstract
- The effect of combining RDC-11 (a new ruthenium organometallic complex) and fast neutrons (high-LET radiations) has been evaluated in RDM4 and U-87 tumor cell lines. After co-treatment, a substantial reduction of cell growth was recorded, which appears not to be correlated with the induction of apoptosis.
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Leyva, L., Malek, F., Benzina, S., Denis, J., Gueulette, J., Dufour, P., Gaiddon, C., Loeffler, J. P., Sirlin, C., Pfeffer, M., & Bischoff, P. (2008). Evaluation of the ability of an organic derivative of ruthenium(II) to reinforce the cytotoxicity of fast neutron against malignant cells in culture. Letters in Drug Design & Discovery, 5(1), 1-6. https://doi.org/10.2174/157018008783406714 (Original work published 2008)