Upper airway obstruction during nasal intermittent positive-pressure hyperventilation in sleep.

Delguste, Pierre;Aubert-Tulkens, G;Rodenstein, Daniel
(1991) The Lancet — Vol. 338, n° 8778, p. 1295-1297 (1991)

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  • Delguste, PierreUCLouvain
    Author
  • Aubert-Tulkens, G
    Author
  • Rodenstein, DanielUCLouvain
    Author
Abstract
Episodes of apnoea for up to 1 min were observed in association with hypocapnia caused by passive nasal intermittent positive-pressure mechanical hyperventilation in 3 of 4 patients during sleep. Apnoea seemed to be caused by complete upper airways obstruction; we suggest that this finding was caused by active glottic closure. Avoidance of excessive hypocapnia during positive-pressure ventilation might help to avoid central-nervous-system mediated apnoeic episodes.
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Delguste, P., Aubert-Tulkens, G., & Rodenstein, D. (1991). Upper airway obstruction during nasal intermittent positive-pressure hyperventilation in sleep. The Lancet, 338(8778), 1295-1297. https://doi.org/10.1016/0140-6736(91)92593-Q (Original work published 1991)