The effect of clinical covariates on the diagnostic and prognostic value of soluble mesothelin and megakaryocyte potentiating factor

Hollevoet, Kevin;Nackaerts, Kristiaan;Thas, Olivier;Thimpont, Joël;van Meerbeeck, Jan P;et.al.
(2012) Chest : the cardiopulmonary and critical care journal — Vol. 141, n° 2, p. 477-484 (2012)

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Authors
  • Hollevoet, Kevin
    Author
  • Nackaerts, Kristiaan
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  • Thas, Olivier
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  • Thimpont, Joël
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  • Legrand, CatherineUCLouvain
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  • van Meerbeeck, Jan P
    Author
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Abstract
SM and MPF levels were affected by the same clinical covariates, which also had a significant impact on their diagnostic and prognostic value. To improve the interpretation of biomarker results, age, GFR, and BMI should be routinely recorded. Approaches to account for these covariates require further validation, as does the prognostic value of SM and MPF.
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Hollevoet, K., Nackaerts, K., Thas, O., Thimpont, J., Germonpré, P., De Vuyst, P., Bosquée, L., Legrand, C., Kellen, E., Kishi, Y., Delanghe, J. R., & van Meerbeeck, J. P. (2012). The effect of clinical covariates on the diagnostic and prognostic value of soluble mesothelin and megakaryocyte potentiating factor. Chest : the cardiopulmonary and critical care journal, 141(2), 477-484. https://doi.org/10.1378/chest.11-0129 (Original work published 2012)