Comparison of outcomes in noncomplicated and in higher-risk donors after standard versus hand-assisted laparoscopic nephrectomy.

Mateo, Rod B;Sher, Linda;Jabbour, Nicolas;Singh, Gagandeep;Genyk, Yuri;et.al.
(2003) American Surgeon — Vol. 69, n° 9, p. 771-778 (2003)

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Authors
  • Mateo, Rod B
    Author
  • Sher, Linda
    Author
  • Jabbour, NicolasUCLouvain
    Author
  • Singh, Gagandeep
    Author
  • Genyk, Yuri
    Author
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Abstract
Hand-assisted techniques facilitated dissemination of the laparoscopic approach in live kidney donors and addressed concerns regarding potential procedural complications. We report our experience with both standard and hand-assisted laparoscopic nephrectomy in routine, complicated, and higher-risk donors. From July 1999 to September 2002, 47 donors underwent standard laparoscopic donor nephrectomy (SLDN; n = 29) or hand-assisted laparoscopic donor nephrectomy (HALDN; n = 18). Donors were "complicated" if they were > 60 years of age, obese, refused blood-product transfusion, had multiple renal arteries or veins, or had right nephrectomies. "Higher-risk" donors had two or more risk factors. Results for SLDN and HALDN were compared for the overall groups and for the "complicated" and "higher-risk" groups. No donor required blood transfusion or reoperation. Warm-ischemia times were shorter in left nephrectomies (191 +/- 72 seconds vs. 337 +/- 95 seconds, P = 0.005), and blood loss was greater in patients with a body mass index > or = 30 kg/m2 (296 +/- 232 mL vs. 170 +/- 139 mL, P = 0.03). Higher-risk donors had an increased operative blood loss and longer hospital stay than low-risk donors. Mean donor creatinine at discharge was 1.19 +/- 0.2 mg/dL. Comparison of SLDN versus HALDN revealed shorter operating times for the latter, which approached statistical significance. Warm-ischemia time, operative blood loss, length of hospitalization, and donor and recipient discharge creatinines were similar for both groups. Laparoscopic donor nephrectomy can be applied to selected higher-risk donors with outcomes comparable to uncomplicated donors. Hand-assisted techniques facilitate the procedure during the learning curve, with advantages similar to standard laparoscopic techniques.
Affiliations
  • Keck School of Medicine, University of Southern California, University Hospital, Los Angeles, USADivision of Hepatobiliary/Pancreatic Surgery and Abdominal Organ Transplantation

Citations

Mateo, R. B., Sher, L., Jabbour, N., Singh, G., Chan, L., Selby, R. R., El-Shahawy, M., & Genyk, Y. (2003). Comparison of outcomes in noncomplicated and in higher-risk donors after standard versus hand-assisted laparoscopic nephrectomy. American Surgeon, 69(9), 771-778. https://hdl.handle.net/2078.5/189439 (Original work published 2003)