Ring closing metathesis of vinyl glycine derivatives using Grubbs' ruthenium catalyst has been performed successfully. The reaction works well with N-allyl amides derived from N-protected vinyl glycines. The use ol: a trityl protecting group allows the reaction to be performed successfully with the otherwise unreactive N-allyl vinyl glycine ester. (C) 1998 Elsevier Science Ltd. All rights reserved.
Campagne, J.-M., & Ghosez, L. (1998). Ring closing metathesis of vinyl glycine derivatives. Tetrahedron Letters, 39(34), 6175-6178. https://doi.org/10.1016/S0040-4039(98)01270-2 (Original work published 1998)