2237P Avelumab (AVE), cetuximab (CET) and irinotecan (IRI) for treatment refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): Translational analyses of the AVETUXIRI phase II trial

Huyghe, Nicolas;Benidovskaya, Elena;Masoodi, Tariq;Carrasco, Javier;Van den Eynde, Marc;et.al.
(2023) ESMO Congress 2023 — Location: (Spain) Madrid (20.October.2023)

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Abstract
BACKGROUND : This trial explores the clinical efficacy and safety of AVE, CET and IRI for treatment refractory MSS mCRC. We aim at characterizing the immune response for biomarker discovery through associated translational research. [...]
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Huyghe, N., Benidovskaya, E., Masoodi, T., Carrasco, J., De Cuyper, A., Sinapi, I., Vempalli, F., Verstraelen, E., Goffette, P., Ghaye, B., Papier, M., Bedognetti, D., van Maanen, A., Castella, M.-L., Galon, J., & Van den Eynde, M. (2023). 2237P Avelumab (AVE), cetuximab (CET) and irinotecan (IRI) for treatment refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): Translational analyses of the AVETUXIRI phase II trial. Annals of Oncology, 34(Suppl 1), S1152. https://doi.org/10.1016/j.annonc.2023.09.1265 (Original work published 2023)