Bone metastases cause considerable morbidity and mortality among patients with genitourinary malignancies. Optimal management requires consideration of bone-targeted therapy as well as disease-specific therapy. Further research is needed to optimize the use of existing agents and to define the therapeutic potential of novel targets.
Saylor, P. J., Armstrong, A. J., Fizazi, K., Freedland, S., Saad, F., Smith, M. R., Tombal, B., & Pienta, K. (2013). New and emerging therapies for bone metastases in genitourinary cancers. European Urology, 63(2), 309-320. https://doi.org/10.1016/j.eururo.2012.10.007 (Original work published 2013)