Concomitant Caffeine Increases Binge Consumption of Ethanol in Adolescent and Adult Mice, But Produces Additive Motor Stimulation Only in Adolescent Animals.
Fritz, Brandon M;Quoilin, Caroline;Kasten, Chelsea R;Smoker, Michael;Boehm, Stephen L
(2016) Alcoholism: Clinical and Experimental Research — Vol. 40, n° 6, p. 1351-1360 (2016)
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Authors
Fritz, Brandon M
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Quoilin, Caroline
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Kasten, Chelsea R
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Smoker, Michael
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Boehm, Stephen L
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Abstract
Binge co-consumption of highly caffeinated energy drinks with alcohol (ethanol [EtOH]) has become a common practice among adolescents/young adults and has been associated with an increased incidence of hazardous behaviors. Animal models are critical in advancing our understanding the neurobehavioral consequences of this form of binge drinking. Surprisingly, virtually no work has explored caffeine and EtOH co-consumption or its long-term consequences in adolescent animals. The primary objective of the current study was to extend a previously established mouse model of voluntary binge caffeine and EtOH co-consumption to explore adolescent consumption and responses compared to adults.
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IUPUIPsychology: Addiction Neuroscience
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Fritz, B. M., Quoilin, C., Kasten, C. R., Smoker, M., & Boehm, S. L. (2016). Concomitant Caffeine Increases Binge Consumption of Ethanol in Adolescent and Adult Mice, But Produces Additive Motor Stimulation Only in Adolescent Animals. Alcoholism: Clinical and Experimental Research, 40(6), 1351-1360. https://doi.org/10.1111/acer.13089 (Original work published 2016)