Chemical constituents of Mallotus macrostachyus growing in Vietnam and cytotoxic activity of some cycloartane derivatives
(2011) Phytochemistry Letters — Vol. 4, n° 3, p. 348-352 (2011)
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- Abstract
- Two new cycloartane derivatives, macrostachyosides A (1) and B (2), and seventeen known compounds were isolated from the methanol extract of Mallotus macrostachyus leaves. Their structures were elucidated by NMR and MS data. Macrostachyosides A (1) and B (2) showed significant cytotoxic activities on KB (epidermoid carcinoma) and LU-1 (lung adenocarcinoma) human cancer cell lines with IC50 values ranging from 4.31 ± 0.09 to 7.12 ± 0.07 μg/mL.
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Hoai Nam, N., Van Kiem, P., Khac Ban, N., Phuong Thao, N., Xuan Nhiem, N., Xuan Cuong, N., Tistaert, C., Dejaegher, B., Vander Heyden, Y., Quetin-Leclercq, J., Thi Thao, D., & Van Minh, C. (2011). Chemical constituents of Mallotus macrostachyus growing in Vietnam and cytotoxic activity of some cycloartane derivatives. Phytochemistry Letters, 4(3), 348-352. https://doi.org/10.1016/j.phytol.2011.07.007 (Original work published 2011)