Objectives: Endoscopic resection (ER) of high-grade dysplasia (HGD) or intramucosal cancer (IMC) in Barrett's esophagus (BE) is an effective and safe alternative to surgical treatment. After ER as monotherapy, recurrent lesions may develop elsewhere in the residual BE during follow-up (FU). Stepwise radical endoscopic resection (SRER) allows for removal of the whole BE by subsequent ERs with histological correlation and has been shown effective and safe in small-sized single-center studies. The aim of this study was to evaluate the efficacy and safety of SRER for BE-HGD/IMC in 4 European tertiary referral centres that used a prospective SRER protocol in the past years.
Gondrie, J. J., Seewald, S., Pouw, R. E., Deprez, P., Piessevaux, H., Pohl, H., Roesch, T., Soehendra, N., & Bergman, J. J. (2009). Stepwise radical endoscopic resection for complete removal of Barrett’s esophagus with early neoplasia: an International multicenter study. European Journal of Gastroenterology and Hepatology, 21(3), A35-A36. https://doi.org/10.1016/j.gie.2008.03.417 (Original work published 2009)