Pancreas transplantation. Combined kidney and pancreas transplantation is one valuable treatment of patients with type I diabetes who developed the long-term secondary complications of the diabetes, with pre-end or end-stage renal disease. Thirteen patients underwent that procedure in our Institution. Technical modifications - such as whole pancreas transplantation with urinary drainage of the exocrine secretion by a pancreatico-duodenocystostomy - allow the monitoring of the exocrine secretion which is a pertinent immunological parameter. In the next future, pancreas transplantation alone should be considered safely using the same procedure, in non uremic diabetic recipients in whom secondary complications would predictably otherwise be more serious than the potential side effects of chronic immunosuppression.
Squifflet, J.-P., & Sutherland, D. E. (1988). La transplantation pancréatique. Acta Chirurgica Belgica (Bilingual Edition), 88(2), 79-85. https://hdl.handle.net/2078.5/69273 (Original work published 1988)