Decreased LV density is associated with high risk of endoscopic recurrence after surgery. Therapies that improve lymphatic flow in the gut may reduce the incidence of endoscopic recurrence.
Rahier, J.-F., Dubuquoy, L., Colombel, J.-F., Jouret-Mourin, A., Delos, M., Ferrante, M., Sokol, H., Hertogh, G. D., Salleron, J., Geboes, K., & Desreumaux, P. (2013). Decreased lymphatic vessel density is associated with postoperative endoscopic recurrence in Crohn’s disease. Inflammatory Bowel Diseases, 19(10), 2084-2090. https://doi.org/10.1097/MIB.0b013e3182971cec (Original work published 2013)