Unusual case of tetraparesis in a patient with systemic lupus erythematosus

Ishchenko, Alla;Malghem, Jacques;Banse, Xavier;Houssiau, Frédéric
(2015) Lupus — Vol. 24, n° 7, p. 760-763 (2015)

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Authors
  • Ishchenko, AllaUCLouvain
    Author
  • Malghem, JacquesUCLouvain
    Author
  • Banse, XavierUCLouvain
    Author
  • Houssiau, FrédéricUCLouvain
    Author
Abstract
We describe the case of a 67-year-old Asian female patient suffering from severe systemic lupus erythematosus (SLE), including biopsy-proven glomerulonephritis, since the age of 40 who was admitted for tetraparesis. Neurological examination confirmed proximal muscular weakness, hypoesthesia and diminished tendon reflexes. The patient suffered from extremely severe Jaccoud's arthropathy. Magnetic resonance imaging (MRI) demonstrated severe narrowing of the upper spinal canal due to a soft tissue mass surrounding the odontoid process, assumed to be a synovial pannus, causing myelopathy. The patient was treated with three intravenous pulses of methylprednisolone with prompt and full clinical recovery. Follow-up MRI confirmed considerable regression of the pannus. Inflammatory transverse myelopathy is the most common explanation for para/tetraparesis in SLE. However, in this case, the symptoms were caused by atlantoaxial synovitis, which is more typical for rheumatoid arthritis.
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Ishchenko, A., Malghem, J., Banse, X., & Houssiau, F. (2015). Unusual case of tetraparesis in a patient with systemic lupus erythematosus. Lupus, 24(7), 760-763. https://doi.org/10.1177/0961203314567752 (Original work published 2015)