Synthesis of Amino-acids - Alkylation of Aldimine and Ketimine Derivatives of Glycine Ethyl-ester Under Various Phase-transfer Conditions

Ghosez, Léon;Antoine, Jean-Pierre;Deffense, Etienne;Navarro, Mirtha;Wojciechowski, Krzysztof;et.al.
(1982) Tetrahedron Letters — Vol. 23, n° 41, p. 4255-4258 (1982)

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Authors
  • Ghosez, LéonUCLouvain
    Author
  • Antoine, Jean-Pierreorcid-logoUCLouvain
    Author
  • Deffense, EtienneUCLouvain
    Author
  • Navarro, MirthaUCLouvain
    Author
  • Libert, ValérieUCLouvain
    Author
  • Wojciechowski, KrzysztofIndiana-Purdue University at Indianapolis
    Author
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Abstract
The Sciff base derived from glycine ethyl ester and p-chlorobenzaldehyde can be alkylated by the ion-pair extraction method as well as under catalytic liquid-liquid or solid-liquid phase-transfer conditions. This imine is compared with the corresponding benzophenone Schiff base.
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Citations

Ghosez, L., Antoine, J.-P., Deffense, E., Navarro, M., Libert, V., O’donnell, M. J., Bruder, W. A., Willey, K., & Wojciechowski, K. (1982). Synthesis of Amino-acids - Alkylation of Aldimine and Ketimine Derivatives of Glycine Ethyl-ester Under Various Phase-transfer Conditions. Tetrahedron Letters, 23(41), 4255-4258. https://doi.org/10.1016/S0040-4039(00)88718-3 (Original work published 1982)