Factors that predict response of patients with hepatitis C virus infection to boceprevir.

Poordad, Fred;Bronowicki, Jean-Pierre;Gordon, Stuart C;Zeuzem, Stefan;Horsmans, Yves;et.al.
(2012) Gastroenterology —

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Authors
  • Poordad, Fred
    Author
  • Bronowicki, Jean-Pierre
    Author
  • Gordon, Stuart C
    Author
  • Zeuzem, Stefan
    Author
  • Horsmans, YvesUCLouvain
    Author
  • et. al.
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Abstract
The CC polymorphism at IL-28B rs12979860 is associated with response to triple therapy and can identify candidates for shorter treatment durations. A ≥ 1 log(10) decrease in HCV RNA at week 4 of therapy is the strongest predictor of a SVR, regardless of polymorphisms in IL-28B.
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Poordad, F., Bronowicki, J.-P., Gordon, S. C., Zeuzem, S., Jacobson, I. M., Sulkowski, M. S., Poynard, T., Morgan, T. R., Molony, C., Pedicone, L. D., Sings, H. L., Burroughs, M. H., Sniukiene, V., Boparai, N., Goteti, V. S., Brass, C. A., Albrecht, J. K., Bacon, B. R., Horsmans, Y., & et al. (2012). Factors that predict response of patients with hepatitis C virus infection to boceprevir. Gastroenterology. https://doi.org/10.1053/j.gastro.2012.05.011