Ossification of a rectal tumor: an uncommon finding.

Smajda, Stanislas;Danse, Etienne;Mertens de Wilmars, Maud;Humblet, Yves;Jouret-Mourin , Anne;et.al.
(2015) Acta Gastro-Enterologica Belgica — Vol. 78, n° 4, p. 431-435 (2015)

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Authors
  • Smajda, StanislasUCLouvain
    Author
  • Danse, EtienneUCLouvain
    Author
  • Mertens de Wilmars, MaudUCLouvain
    Author
  • Humblet, YvesUCLouvain
    Author
  • Kartheuser, AlexUCLouvain
    Author
  • Jouret-Mourin , AnneUCLouvain
    Author
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Abstract
The authors report the case of a 29-year-old woman with partially calcified stage cT4N2M0 mucoid adenocarcinoma of the mid-rectum. Concomitant neoadjuvant chemoradiotherapy was administered. Preoperative CT scan and MRI demonstrated stable disease with a marked increase of its mineralized component. Histology confirmed a mucoid adenocarcinoma with ossified matrix. Osteocytes were identified in the tumor. TNM (5th edition) staging was ypT3N2M1. This case illustrates heterotopic ossification of a rectal tumor, a fairly uncommon finding. The mechanism of heterotopic bone formation within gastrointestinal adenocarcinoma has not been fully elucidated. The impact of this particular feature on patient outcome is unknown.
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Smajda, S., Danse, E., Mertens de Wilmars, M., Humblet, Y., Kartheuser, A., & Jouret-Mourin, A. (2015). Ossification of a rectal tumor: an uncommon finding. Acta Gastro-Enterologica Belgica, 78(4), 431-435. https://hdl.handle.net/2078.5/66428 (Original work published 2015)