(en) TO THE EDITOR : The late asthmatic response (LAR) occurring during experimental allergic asthma is a recognized model for the study of asthma mechanisms. It involves inflammatory processes, such as eosinophil recruitment and activation and mast cell and basophil activation, and activated lymphocytes and their Th2 cytokines. It has been suggested that protective anti-inflammatory mechanisms, particularly Treg, are defective during the LAR phase. [...]
Doyen, V., Poirot, A., Maumy-Bertrand, M., Bertrand, F., Khayath, N., Domis, N., & de Blay, F. (2023). Induction of immunosuppressive CD39 but not the trafficking C-C chemokine receptor 4 on Treg during LAR in mite allergic asthma. Allergy, 78(7), 2031-2033. https://doi.org/10.1111/all.15681 (Original work published 2023)