Living-related liver transplantation in children at Saint-Luc University Clinics: a seven year experience in 77 recipients.
(2001) Acta Chirurgica Belgica (Bilingual Edition) — Vol. 101, n° 1, p. 17-19 (2001)
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- Abstract
- The Brussels series of living related liver transplantation (LRLT) in 77 children (< 15 years) is reviewed. Median (range) recipient age at liver transplantation was 1.1 year (0.4-13.1). The main indication for LT was biliary atresia in 55/77 cases (71%). The living-related donor was one of the parents in 74 instances. Hepatic segments 2-3 (n = 67) or 2-3-4 (n = 10) were implanted orthotopically, with a median (range) graft weight to recipient body weight ratio of 3.17% (0.91-8.08). No severe complications or significant long-term sequelae were encountered in the living donors. One and five year survival rates were 92% and 89% for the patients, and 90% and 86% for the grafts, respectively. The retransplantation rate was 2/77 (2.6%), the indication being chronic rejection in both instances. In conclusion, LRLT is now a validated procedure in the living donors as well as in pediatric recipients with chronic or acute liver diseases. In the current context of organ shortage, it provides a valuable alternative to cadaveric LT.
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Reding, R., Chardot, Chr., Paul, K., Veyckemans, F., Van Obbergh, L., Clement De Clety, S., Detaille, T., Clapuyt, P., Saint-Martin, Chr., Janssen, M., Lerut, J., Sokal, E., & Otte, J.-B. (2001). Living-related liver transplantation in children at Saint-Luc University Clinics: a seven year experience in 77 recipients. Acta Chirurgica Belgica (Bilingual Edition), 101(1), 17-19. https://hdl.handle.net/2078.5/131209 (Original work published 2001)