Preeclampsia and blood lead (and other metals) in Lubumbashi, DR Congo.

Musa Obadia, Paul;Kayembe-Kitenge, Tony;Haufroid, Vincent;Banza Lubaba Nkulu, Célestin;Nemery, Benoit
(2018) Environmental Research — Vol. 167, p. 468-471 (2018)

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Authors
  • Musa Obadia, Paul
    Author
  • Kayembe-Kitenge, Tony
    Author
  • Author
  • Banza Lubaba Nkulu, Célestin
    Author
  • Nemery, Benoit
    Author
Abstract
Among parturient women in Lubumbashi, blood lead concentrations [geometric means (25th-75th percentiles)] were higher among 40 women with preeclampsia [6.66 µg/dL (5.16-79.4)] than among 39 control women matched for age and gestation duration [5.08 µg/dL (4.27-6.30)]. Blood lead exceeded 5 µg/dL in 33 (83%) preeclamptic women and 17 (44%) control women [odds ratio 6.1 (95%CI 2.1-17.1)]. In another study, we found high levels of lead in surface dust collected in front of homes in Lubumbashi (36/127 samples exceeding 120 µg lead/g dust). Our findings support the conclusions of a systematic review that increased blood lead level increases the likelihood of preeclampsia. Moreover, our study indicates that, as in other urban areas in Africa, exposure to lead is unacceptably high among pregnant women in Lubumbashi. Preventive measures are needed to protect mothers and children from the serious adverse effects of lead exposure.
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Citations

Musa Obadia, P., Kayembe-Kitenge, T., Haufroid, V., Banza Lubaba Nkulu, C., & Nemery, B. (2018). Preeclampsia and blood lead (and other metals) in Lubumbashi, DR Congo. Environmental Research, 167, 468-471. https://doi.org/10.1016/j.envres.2018.07.032 (Original work published 2018)