Mesenchymal cells: metalloproteinases and adhesion on microcarriers

Mosbeux, C.;Pedregal, A. R. dos Santos;Sousa, D. Ribeiro;Hendric, Vincianne;Werenne, J.;et.al.
(2006) ISBN: [9781402044571], 7 pages, published

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Authors
  • Mosbeux, C.Laboratory of Animal Cell Biotechnology. Dept. of Bioengineering, Université Libre de Bruxelles, Belgium
    Author
  • Pedregal, A. R. dos SantosLaboratory of Animal Cell Biotechnology. Dept. of Bioengineering, Université Libre de Bruxelles, Belgium
    Author
  • Sousa, D. RibeiroLaboratory of Animal Cell Biotechnology. Dept. of Bioengineering, Université Libre de Bruxelles, Belgium
    Author
  • Hendric, VincianneLaboratory of Animal Cell Biotechnology. Dept. of Bioengineering, Université Libre de Bruxelles, Belgium
    Author
  • Bensellam, Mohammedorcid-logoUCLouvain
    Author
  • Werenne, J.Laboratory of Animal Cell Biotechnology. Dept. of Bioengineering, Université Libre de Bruxelles, Belgium
    Author
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Abstract
The purpose of this work was to approach the development of a safe and validable process to grow the amounts of adult Mesenchymal Stem Cells (MSC) necessary for future biomedical applications. Using a single use Vue Life bag system integrated in a simple agitations bioreactor we constructed, we have studied the adhesion, migration and growth properties of MSC on different carriers (Cytodex and Bionoc) in comparison to other cells (endothelial/Kaposi sarcoma cells, CHO and HeLa) in relation to the expression of endogenous Metalloproteinases.
Affiliations
  • Université Libre de Bruxelles

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Mosbeux, C., Pedregal, A. R. d. S., Sousa, D. R., Hendric, V., Joseph, N., Bensellam, M., Blankaert, D., Marique, T., Alloin, C., Parent, D., Liesnard, C., Vooren, J. P. V., Lowagie, S., & Werenne, J. (2006). Mesenchymal cells: metalloproteinases and adhesion on microcarriers. Shinji Iijima, Ken-Ichi Nishijima. https://doi.org/10.1007/1-4020-4457-7_1