Objective: Investigating the influence of dopamine on motor inhibition during action preparation. Background: By measuring the amplitude of motor-evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) during choice reaction time (RT) tasks, many studies have revealed a strong suppression of corticospinal excitability during action preparation. This phenomenon, called preparatory inhibition, has never been investigated in Parkinson’s disease (PD). Yet, it would allow addressing the role of dopamine in the generation of preparatory inhibition. [...]
Wilhelm, E., Quoilin, C., Derosiere, G., Jeanjean, A., & Duque, J. (2019). The role of Dopamine in Preparatory Inhibition: What can we learn from Parkinson’s disease? Movement Disorders, 34(Suppl 2), S465. https://hdl.handle.net/2078.5/93868 (Original work published 2019)