Adenomatoid tumors are benign tumors of mesothelial origin that are usually encountered in the genital tract. Although they have been observed in other organs, the skin appears to be a very rare location, with only one case reported in the literature to our knowledge. We report a second case of an adenomatoid tumor, arising in the umbilicus of a 44-year-old woman. The patient presented with an 8-month-old erythematous and firm plaque under the umbilicus. A skin biopsy showed numerous microcystic spaces dissecting a fibrous stroma and lined by flattened to cuboidal cells with focal intraluminal papillary formation. This little-known diagnosis constitutes a diagnostic pitfall for dermatopathologists and dermatologists, and could be misdiagnosed as other benign or malignant entities. Through this case report, a practical approach and diagnostic keys have been devised to avoid misdiagnosis and overtreatment.
Ferreira de Castro Moutinho, I., De Lathouwer, O., Fierens, H., Theunis, A., André, J., & de Saint Aubain, N. (2021). Adenomatoid tumor of the skin: Differential diagnosis of an umbilical erythematous plaque. Journal of Cutaneous Pathology, 48(1), 128-132. https://doi.org/10.1111/cup.13872 (Original work published 2021)