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Study claiming target in sepsis with erythromycin has no effect upon mortality and secondary outcomes includes patients with CRRT and RRT.

Honoré, Patrick;Blackman, Sydney;Perriens, Emily;Bousbiat, Ibrahim
(2023) Critical Care — Vol. 27, n° 1, p. 52 [1-2] (2023)

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Authors
  • Author
  • Blackman, Sydney
    Author
  • Perriens, Emily
    Author
  • Bousbiat, Ibrahim
    Author
Abstract
(en) Reijnders et al. recently published an article concluding that, in their target trial emulation on critically ill patients with sepsis, they could not demonstrate an effect of treatment with low-dose erythromycin on mortality, secondary clinical outcomes, or host response biomarkers. However, when carefully reviewing the baseline characteristics, we found that 49.8% of the patients in the treated group had acute kidney injury (AKI). [...]
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Citations

Honoré, P., Blackman, S., Perriens, E., & Bousbiat, I. (2023). Study claiming target in sepsis with erythromycin has no effect upon mortality and secondary outcomes includes patients with CRRT and RRT. Critical Care, 27(1), 52 [1-2]. https://doi.org/10.1186/s13054-023-04335-7 (Original work published 2023)