Total DNA from five Campylobacter species was digested with a mixture of XhoI and BglII restriction endonucleases and analyzed by Southern hybridization by using a probe complementary to the DNA coding for the 16S rRNA. Each of the Campylobacter species, including C. jejuni, C. coli, C. laridis, C. fetus, and C. upsaliensis, displayed a characteristic pattern. Although some bands may be common to different species, the simplicity of the hybridization pattern enabled us to discriminate among the different species of Campylobacter.
Moureau, P., Derclaye, I., Grégoire, D., Janssen, M., & Cornelis, G. R. (1989). Campylobacter species identification based on polymorphism of DNA encoding rRNA. Journal of Clinical Microbiology, 27(7), 1514-1517. https://hdl.handle.net/2078.5/78382 (Original work published 1989)