Phagocytosis and killing of intracellular pathogens: interaction between cytokines and antibiotics.

Ouadrhiri, Youssef;Sibille, Yves
(2000) Current Opinion in Infectious Diseases — Vol. 13, n° 3, p. 233-240 (2000)

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  • Ouadrhiri, Youssef
    Author
  • Sibille, YvesUCLouvain
    Author
Abstract
Phagocytosis and bacterial killing are the primary functions of macrophages. Among the mechanisms involved in the phagocytic process, cytokines, especially those of T-helper 1 profile, appear to influence considerably the internalization and the intracellular fate of the pathogen within the macrophage. In particular, the evidence for a cooperation of cytokines with antibiotics in intracellular infection could provide new therapeutic approaches to intracellular infectious diseases in the future.
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Ouadrhiri, Y., & Sibille, Y. (2000). Phagocytosis and killing of intracellular pathogens: interaction between cytokines and antibiotics. Current Opinion in Infectious Diseases, 13(3), 233-240. https://hdl.handle.net/2078.5/28725 (Original work published 2000)