Rapid identification of OXA-48 and OXA-163 subfamily in carbapenem resistant gram-negative bacilli with a novel immunochromatographic lateral flow assay.
(2016) Journal of Clinical Microbiology — Vol. 54, n° 11, p. 2832-2836 (2016)
Files
PasteranFJClinMicrobiol2016.pdf
Open Access - Adobe PDF
- 421.53 KB
Details
- Authors
- Abstract
- We assessed a novel immunochromatographic lateral flow assay for direct identification of OXA-48-like carbapenemases and accurate differentiation of allele variants with distinct substrate profiles (OXA-48 or OXA-163 subfamilies). The assay allows rapid (less than 4 minutes) and reliable direct confirmation of OXA-163/48-like enzymes (100% sensitivity and specificity) from culture colonies recovered from both, solid media and spiked blood culture bottles.
- Affiliations
Citations
Pasteran, F., Denorme, L., Ote, I., Gomez, S., De Belder, D., Glupczynski, G., Bogaerts, P., Ghiglione, B., Power, P., Mertens, P., & Corso, A. (2016). Rapid identification of OXA-48 and OXA-163 subfamily in carbapenem resistant gram-negative bacilli with a novel immunochromatographic lateral flow assay. Journal of Clinical Microbiology, 54(11), 2832-2836. https://doi.org/10.1128/JCM.01175-16 (Original work published 2016)