Effect of interferon-alpha-based antiviral therapy on hepatitis C virus-associated glomerulonephritis: a meta-analysis.

Feng, Bo;Eknoyan, Garabed;Guo, Zhong-Sheng;Jadoul, Michel;Wei, Lai;et.al.
(2012) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association — Vol. 27, n° 2, p. 640-646 (2012)

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Authors
  • Feng, Bo
    Author
  • Eknoyan, Garabed
    Author
  • Guo, Zhong-Sheng
    Author
  • Jadoul, MichelUCLouvain
    Author
  • Wei, Lai
    Author
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Abstract
Antiviral therapy based on IFNα can significantly decrease proteinuria and stabilize serum creatitine, and therefore, should be undertaken in patients with HCV-associated glomerulonephritis. The improvement in protein excretion is greater in those who achieve HCV RNA clearance, a finding in line with a causal role for HCV in glomerulonephritis.
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Feng, B., Eknoyan, G., Guo, Z.-S., Jadoul, M., Rao, H.-Y., Zhang, W., & Wei, L. (2012). Effect of interferon-alpha-based antiviral therapy on hepatitis C virus-associated glomerulonephritis: a meta-analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 27(2), 640-646. https://doi.org/10.1093/ndt/gfr236 (Original work published 2012)