Cubilin and amnionless protein are novel target antigens in anti-brush border antibody disease.

Morelle, Johann;Caza, Tiffany;Debiec, Hanna;Aydin, Selda;Larsen, Christopher;et.al.
(2022) Kidney International — Vol. 101, n° 5, p. 1063-1068 (2022)

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(en) The kidney proximal tubule reabsorbs large amounts of low-molecular-weight proteins, albumin, electrolytes, and solutes from the glomerular filtrate to the systemic circulation. Alteration of the specialized transport systems that operate in the brush border of proximal tubule cells leads to urinary loss of these molecules and compromises homeostasis. [...]
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Morelle, J., Caza, T., Debiec, H., Aydin, S., Storey, A., Ronco, P., & Larsen, C. (2022). Cubilin and amnionless protein are novel target antigens in anti-brush border antibody disease. Kidney International, 101(5), 1063-1068. https://doi.org/10.1016/j.kint.2022.02.021 (Original work published 2022)