Biodegradation of nitro-substituted explosives by white-rot fungi : a mechanistic approach
(2001) Advances in Applied Microbiology — Vol. 48, p. 1-77 (2001)
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- Authors
Agathos, Spiros N. 
- Abstract
- (en) P. chrysosporium remains the most widely studied model organism in both basic and applied research on degradation of lignin and xenobiotic pollutants. P. chrysosporium presents the advantages of a rapid growth in liquid defined media, of a high metabolic activity, and of an asexual reproduction by conidia spores. Biodegradation of xenobiotic pollutants by white-rot fungi requires a close contact between contaminants and the fungal mycelium, adequate aeration, and nutrient limitation in order to induce the ligninolytic system. Fungal ligninolysis by itself is therefore a cometabolic and nonproductive mechanism. This unique and powerful system, which seems to be the exclusive property of white rot fungi, involves reactive (radical) species harmful for biological systems. White-rot fungi possess membrane-associated reduction system(s) likely implicated in protection/detoxification purposes, but which seem(s) not to play any direct role in the ligninolysis process. The bioremediation techniques using white-rot fungi that reside in the exploitation of side reactions is associated to two distinct mechanisms: one oxidative and one reductive. Fungal biodegradation in field experiments may involve numerous additional factors susceptible to interfere with the degradative enzymes or to react with the intermediates
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Citations
Van Aken, B., & Agathos, S. N. (2001). Biodegradation of nitro-substituted explosives by white-rot fungi : a mechanistic approach. Advances in Applied Microbiology, 48, 1-77. https://doi.org/10.1016/S0065-2164(01)48000-2 (Original work published 2001)