Major trazodone overdose may be followed by prolonged hypotension and sustained central nervous system (CNS) depression. The treatment of trazodone overdose is mainly supportive, but, as the molecule is lipophilic, we used intravenous lipid emulsion (ILE) in a recent case to minimize the risk of cardiovascular and CNS toxicity. [...]
Nendumba, G., Boland, L., Haufroid, V., Laterre, P.-F., & Hantson, P. (2022). Intravenous Lipid Emulsion in a Case of Trazodone Overdose. Primary Care Companion to C N S Disorders, 24(2), 21cr03113. https://doi.org/10.4088/PCC.21cr02994 (Original work published 2022)