Unrelated living donor kidney transplantation
(1990) New Developments in solid organ transplantation — p. 31-45, published
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- Authors
Gianello, Pierre 
- Abstract
- Since 1966, we have performed 41 renal transplants from unrelated living donors (ULD) (39 were emotionally related"). All ABOcompatible recipients were included in the present series primary (37) and secondary (4) transplants, diabetics (2). We compared their results to those of 41 recipients of cadaver donor kidneys matched for age, sex, immunosuppressive regimen, rank and year of transplant, focusing the discussion on the subgroups of patients (24) under Cyclosporin A (CsA) therapy. ULD transplantation is as successful as cadaver transplantation with a good HLA matching: at 3 years, graft survival rates are 81 % in ULD versus 86 \ in the control group under CsA. Moreover, grafts from ULD functioned more rapidly (no post-transplant dialysis and 70 % of the patients with serum creatinine below 2 mg/dl within 3 days post-transplant). Graft · tolerance was equivalent in both groups (50 \ of patiens without rejection). Despite poor HLA matching, ULD tansplantation under CsA as the basic immunosuppressive agent, offers good results benefit ting from the quality of living donor kidney graft, it helps to alleviate the persisting shortage of cadaver donors.
- Affiliations
Citations
Squifflet, J.-P., Pirson, Y., Poncelet, A., Gianello, P., & Alexandre, G. (1990). Unrelated living donor kidney transplantation. In Boerhaave Committee for Postgraduate Medical Eduction (ed.), New Developments in solid organ transplantation (p. p. 31-45). Dr F.H.J. Claas, Dr H.G. Gooszen, Dr F.J. van der Woude. https://hdl.handle.net/2078.5/224151