Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion.
(2003) Antimicrobial Agents and Chemotherapy — Vol. 47, n° 6, p. 2015-2017 (2003)
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- Abstract
- Blood and pleural exudate samples were obtained from 16 patients receiving intermittent or continuous infusions of vancomycin after lung surgery. The areas under the concentration-time curves for blood and pleural exudates were identical for both administration schedules, while continuous infusion allowed the concentrations in pleural exudates to be more sustained (mean concentration, 12 mg/liter).
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Citations
Byl, B., Jacobs, F., Wallemacq, P., Rossi, C., de Francquen, P., Cappello, M., Leal, T., & Thys, J.-P. (2003). Vancomycin penetration of uninfected pleural fluid exudate after continuous or intermittent infusion. Antimicrobial Agents and Chemotherapy, 47(6), 2015-2017. https://doi.org/10.1128/AAC.47.6.2015-2017.2003 (Original work published 2003)