Heavy chains of striated muscles myosins in NMRI mice on hypocaloric diet
(1991) Réunion de la Société belge de physiologie et de pharmacologie — Location: Gent (3.November.1990)
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- Authors
Maréchal, Georges 
- Abstract
- Male NMRI mice 60 days old were submitted to a hypocaloric diet consisting in a 40% restriction of the mean spontaneous intake. They lost about 15% weight in 7-10 d; animals used for a longer term experimental (49 d) stabilized their weight. The myosin heavy chains (MHC) were separated by gel electrophoresis (SDS-PAGE 5%) and the proportion of the different MHC's was determined by densitometry of the gels. In extensor digitorum longus (EDL, a fast muscle) the proportion of MHC2A increased after 9 d caloric restriction and that the difference is still more apparent after 49 d. There is a slight non-significant increase of MHC2A in soleus, a slow muscle. Hypocaloric diet slows down markedly fast muscles (EDL) and moderately slow muscles (Soleus).
Citations
Halleux, G., Maréchal, G., & Godfraind-De Becker, A. (1991). Heavy chains of striated muscles myosins in NMRI mice on hypocaloric diet. Arch Int Physiol Biochim, 99(2), p34. https://hdl.handle.net/2078.5/214502 (Original work published 1991)