Patterns and Predictors of Early Biochemical Recurrence After Radical Prostatectomy and Adjuvant Radiation Therapy in Men With pT3N0 Prostate Cancer: Implications for Multimodal Therapies.

Briganti, Alberto;Joniau, Steven;Gandaglia, Giorgio;Cozzarini, Cesare;Wiegel, Thomas;et.al.
(2013) International Journal of Radiation: Oncology - Biology - Physics — Vol. 87, n° 5, p. 960-967 (2013)

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Authors
  • Briganti, Alberto
    Author
  • Joniau, Steven
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  • Gandaglia, Giorgio
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  • Cozzarini, Cesare
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  • Tombal, Bertrandorcid-logoUCLouvain
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  • Wiegel, Thomas
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Abstract
High Gleason score represents the only predictor of eBCR after RP and aRT in patients affected by pT3N0 PCa. Given the association between early PSA recurrence, clinical progression, and mortality, these patients might be considered candidates for adjuvant medical therapy and/or prophylactic whole-pelvis radiation therapy in addition to aRT, delivered to the prostatic bed.
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Briganti, A., Joniau, S., Gandaglia, G., Cozzarini, C., Sun, M., Tombal, B., Haustermans, K., Hinkelbein, W., Shariat, S. F., Karakiewicz, P. I., Montorsi, F., Van Poppel, H., & Wiegel, T. (2013). Patterns and Predictors of Early Biochemical Recurrence After Radical Prostatectomy and Adjuvant Radiation Therapy in Men With pT3N0 Prostate Cancer: Implications for Multimodal Therapies. International Journal of Radiation: Oncology - Biology - Physics, 87(5), 960-967. https://doi.org/10.1016/j.ijrobp.2013.09.015 (Original work published 2013)