Nuclear medicine practice in the field of infection and inflammation imaging: a pragmatical survey.

Annunziata, Salvatore;Treglia, Giorgio;Jamar, François;Lauri, Chiara;Glaudemans, Andor W J M;et.al.
(2022) European Journal of Nuclear Medicine and Molecular Imaging — Vol. 49, n° 7, p. 2113-2119 (2022)

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Abstract
(en) During the last decade, the interest in nuclear medicine techniques for diagnosing infections has been growing. There is an increasing body of evidence to support the use of [18F]-FDG positron emission tomography/computed tomography ([18F]-FDG-PET/CT) for several indications in this field. Nevertheless, [18F]-FDG has some important limitations and pitfalls, especially in patients with foreign body material. In these cases, differentiation between reactive inflammation and infection can be challenging and a correct diagnosis is of utmost importance for subsequent treatment. For these cases, white blood cell (WBC) scintigraphy is a highly valuable technique that allows for the visualization of the dynamics of white blood cells, hence differentiation between sterile inflammation and infection with high accuracy. [...]
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Annunziata, S., Treglia, G., Jamar, F., Lauri, C., Palestro, C. J., Gheysens, O., & Glaudemans, A. W. J. M. (2022). Nuclear medicine practice in the field of infection and inflammation imaging: a pragmatical survey. European Journal of Nuclear Medicine and Molecular Imaging, 49(7), 2113-2119. https://doi.org/10.1007/s00259-022-05725-9 (Original work published 2022)