A case of primary chronic sclerosing osteomyelitis of the fibula in a 14-year-old is described. This rare condition can be difficult to differentiate from a bone tumor. Its pathogenesis is controversial, although the prevalent hypothesis involves chronic osteomyelitis developing after an unrecognized phase of acute infection. The existence of primary chronic sclerosing osteomyelitis as a disease in its own right has been challenged. Recently, primary chronic sclerosing osteomyelitis has been interpreted as a localized or monofocal variant of multifocal recurrent chronic osteitis or of the bone abnormalities associated with seronegative spondyloarthropathies (SAPHO syndrome). (C) 2004 Published by Elsevier SAS.
Viejo-Fuertes, D., Mousny, M., Lecouvet, F., Rossillon, R., Docquier, P.-L., & Rombouts, J.-J. (2005). Primary chronic sclerosing osteomyelitis - a case-report. Joint Bone Spine, 72(1), 73-75. https://doi.org/10.1016/j.jbspin.2004.02.007 (Original work published 2005)