Characterization of the CtsR stress response regulon in Lactobacillus plantarum.

Fiocco, Daniela;Capozzi, Vittorio;Collins, Michael;Gallone, Anna;Spano, Giuseppe;et.al.
(2010) Journal of bacteriology — Vol. 192, n° 3, p. 896-900 (2010)

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Authors
  • Fiocco, Daniela
    Author
  • Capozzi, Vittorio
    Author
  • Collins, Michael
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  • Gallone, Anna
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  • Hols, Pascalorcid-logoUCLouvain
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  • Spano, Giuseppe
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Abstract
Lactobacillus plantarum ctsR was characterized. ctsR was found to be cotranscribed with clpC and induced in response to various abiotic stresses. ctsR deletion conferred a heat-sensitive phenotype with peculiar cell morphological features. The transcriptional pattern of putative CtsR regulon genes was examined in the DeltactsR mutant. Direct CtsR-dependent regulation was demonstrated by DNA-binding assays using recombinant CtsR and the promoters of ctsR-clpC operon and hsp1.
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Fiocco, D., Capozzi, V., Collins, M., Gallone, A., Hols, P., Guzzo, J., Weidmann, S., Rieu, A., Msadek, T., & Spano, G. (2010). Characterization of the CtsR stress response regulon in Lactobacillus plantarum. Journal of bacteriology, 192(3), 896-900. https://doi.org/10.1128/JB.01122-09 (Original work published 2010)