Ethical and legal considerations of digital animal models: pioneering reduction and replacement
(2025) Trends in Biotechnology — p. 1-3 (2025)
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- Authors
Germani, Federico 
März, Julian W. Luciani, Alessandro Biller-Andorno, Nikola
- Abstract
- The development of digital animal models represents a promising avenue for advancing the ethical principles of reduction and replacement in biomedical research. This paper discusses the potential of models built upon artificial intelligence (AI)-generated synthetic datasets simulating the characteristics and behaviors of model organisms, reducing reliance on live animals in research.
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Citations
Germani, F., März, J. W., Luciani, A., Devuyst, O., & Biller-Andorno, N. (2025). Ethical and legal considerations of digital animal models: pioneering reduction and replacement. Trends in Biotechnology, 1-3. https://doi.org/10.1016/j.tibtech.2025.08.011 (Original work published 2025)