Colorectal cancer metastases harbour distinct microbial signature shared with the primary tumors

(2026) Belgian Week of Gastroenterology 2026 - 38th edition — Location: Antwerp, Belgium (11.February.2026)

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Abstract
This work aims to characterize tumor-resident bacteria in colorectal cancer (CRC) metastases, matched primary tumors, and in a control group of non-CRC tumors (liver PT and non-CRC liver MT) through different methodologies (16s rRNA gene sequencing and fluorescent in situ hybridization). Our analyses revealed a consistent and distinct microbial signature in metastatic CRC, along with a potential bacterial dissemination during cancer progression.
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Deneft, J., & et al. (2026). Colorectal cancer metastases harbour distinct microbial signature shared with the primary tumors. Belgian Week of Gastroenterology 2026 - 38th edition, Antwerp, Belgium. https://hdl.handle.net/2078.5/272072