Imidazolopyrazinones as potential antioxidants.

Devillers, I;Dive, G.;De Tollenaere, C;Falmagne, B;Marchand-Brynaert, Jacqueline;et.al.
(2001) Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology — Vol. 11, n° 17, p. 2305-2309 (2001)

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Authors
  • Devillers, I
    Author
  • Dive, G.
    Author
  • De Tollenaere, C
    Author
  • Falmagne, B
    Author
  • Author
  • Marchand-Brynaert, JacquelineUCLouvain
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Abstract
A series of imidazolopyrazinones 3, substituted at C-2, and C-2/C-6, has been prepared. The compounds behaved as quenchers of superoxide anion. The more active compounds are structurally related to coelenterazine, a natural substrate of marine bioluminescence. Theoretical parameters based on Hartree-Fock instabilities have been examined.
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Devillers, I., Dive, G., De Tollenaere, C., Falmagne, B., de Wergifosse, B., Rees, J.-F., & Marchand-Brynaert, J. (2001). Imidazolopyrazinones as potential antioxidants. Bioorganic & Medicinal Chemistry Letters : the tetrahedron journal for research at the interface of chemistry and biology, 11(17), 2305-2309. https://doi.org/10.1016/S0960-894X(01)00445-0 (Original work published 2001)