A Three-Month Consumption of Eggs Enriched With ω-3, ω-5 and ω-7 Polyunsaturated Fatty Acids Significantly Decreases the Waist Circumference of Subjects at Risk of Developing Metabolic Syndrome: A Double-Blind Randomized Controlled Trial

Ngo Njembe, Monique T.;Pachikian, Barbara;Lobysheva, Irina;Van Overstraeten, Nancy;Larondelle, Yvan;et.al.
(2021) Nutrients — Vol. 13, n° 2, p. 663 [1-17] (2021)

Files

nutrients-13-00663.pdf
  • Open Access
  • Adobe PDF
  • 565.81 KB
Download

Details

Authors
  • Ngo Njembe, Monique T.UCLouvain
    Author
  • Pachikian, BarbaraUCLouvain
    Author
  • Lobysheva, Irinaorcid-logoUCLouvain
    Author
  • Van Overstraeten, Nancyorcid-logoUCLouvain
    Author
  • Dejonghe, LouisUCLouvain
    Author
  • Verstraelen, EleonoreUCLouvain
    Author
  • Buchet, MarineUCLouvain
    Author
  • Rasse, CatherineUCLouvain
    Author
  • Gardin, CécileUCLouvain
    Author
  • Mignolet, EricUCLouvain
    Author
  • Balligand, Jean-LucUCLouvain
    Author
  • Larondelle, Yvanorcid-logoUCLouvain
    Author
Show more
Abstract
Alpha-linolenic acid (ALA), docosahexaenoic acid (DHA), rumenic acid (RmA), and punicic acid (PunA) are claimed to influence several physiological functions including insulin sensitivity, lipid metabolism and inflammatory processes. In this double-blind randomized controlled trial, we investigated the combined effect of ALA, DHA, RmA and PunA on subjects at risk of developing metabolic syndrome. Twenty-four women and men were randomly assigned to two groups. Each day, they consumed two eggs enriched with oleic acid (control group) or enriched with ALA, DHA, RmA, and PunA (test group) for 3 months. The waist circumference decreased significantly (-3.17 cm; p < 0.001) in the test group. There were no major changes in plasma insulin and blood glucose in the two groups. The dietary treatments had no significant effect on endothelial function as measured by peripheral arterial tonometry, although erythrocyte nitrosylated hemoglobin concentrations tended to decrease. The high consumption of eggs induced significant elevations in plasma low-density lipoprotein (LDL)- and high-density lipoprotein (HDL)-cholesterol (p < 0.001), which did not result in any change in the LDL/HDL ratio in both groups. These results indicate that consumption of eggs enriched with ALA, DHA, RmA and PunA resulted in favorable changes in abdominal obesity without affecting other factors of the metabolic syndrome.
Affiliations

Citations

  • APA
  • Chicago
  • FWB

Ngo Njembe, M. T., Pachikian, B., Lobysheva, I., Van Overstraeten, N., Dejonghe, L., Verstraelen, E., Buchet, M., Rasse, C., Gardin, C., Mignolet, E., Balligand, J.-L., & Larondelle, Y. (2021). A Three-Month Consumption of Eggs Enriched With ω-3, ω-5 and ω-7 Polyunsaturated Fatty Acids Significantly Decreases the Waist Circumference of Subjects at Risk of Developing Metabolic Syndrome: A Double-Blind Randomized Controlled Trial. Nutrients, 13(2), 663 [1-17]. https://doi.org/10.3390/nu13020663 (Original work published 2021)