The poisoned donors
(1999) Current Opinion in Organ Transplantation — Vol. 4, n° 2, p. 125 (1999)
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- Abstract
- An increasing gap exists between the demand for organs for transplantation and the availability of grafts. In an attempt to increase the transplant donor pool, “marginal” donors are now considered. Among these donors, poisoned people probably represent an extreme minority; however, an analysis of the recent literature shows successful organ transplantations with grafts obtained from donors poisoned with tricyclic antidepressants, benzodiazepines, barbiturates, insulin, carbon monoxide, methanol, and other substances. Experience indicates that in select cases, the organs from such donors function as well in recipients as organs from more conventional sources. A diagnosis of brain death can be made after careful analysis of toxicologic data. The use of electrophysiologic techniques (multimodality-evoked potentials in complement to electroencephalography) and angiography is recommended to ascertain the diagnosis of brain death.
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Hantson, P. (1999). The poisoned donors. Current Opinion in Organ Transplantation, 4(2), 125. https://hdl.handle.net/2078.5/52076 (Original work published 1999)