The Melody™ valve provides an adaptable solution for mitral valve replacement in infants, allowing for staged expansion and valve-in-valve strategies. Despite a notable risk of AV block, the long-term outcomes are promising, especially in patients too small for conventional prostheses. Close follow-up and further multicenter studies are needed to optimize patient selection and long-term management.
Hubrechts, J., Cools, B., Heying, R., Eyskens, B., Rega, F., Meyns, B., & Gewillig, M. (2025). Long-Term Results of the Melody Valve in the Left Atrioventricular Valve Position in Very Young Children. World Journal for Pediatric and Congenital Heart Surgery, 140(02), 65-76. https://doi.org/10.1177/21501351251391755 (Original work published 2025)