Structural Determinants of Raft Partitioning for Single-Pass Transmembrane Proteins

Lorent, Joseph;Diaz-Rohrer, Barbara B.;Levental, Kandice R.;Levental, Ilya
(2016) 60th Biophysical Society meeting — Location: (United States) Los Angeles, CA (27.February.2016)

Files

2016_BiophysicalSociety_1023-Plat.pdf
  • Open Access
  • Adobe PDF
  • 39.03 KB

Details

Authors
  • Author
  • Diaz-Rohrer, Barbara B.
    Author
  • Levental, Kandice R.
    Author
  • Levental, Ilya
    Author
Abstract
Transmembrane proteins (TMPs) comprise ∼30% of the mammalian proteome and mediate nearly all functions of the cell. The subcellular localization, trafficking, signalling, and enzymatic activity of many TMPs is regulated by their association with lipid-driven lateral membrane domains known as lipid rafts. [...]
Affiliations
  • University of Texas Health Science Center at HoustonDepartment of Integrative Biology and Pharmacology

Citations

Lorent, J., Diaz-Rohrer, B. B., Levental, K. R., & Levental, I. (2016). Structural Determinants of Raft Partitioning for Single-Pass Transmembrane Proteins. Biophysical Journal, 110(3), 205a. https://doi.org/10.1016/j.bpj.2015.11.1144 (Original work published 2016)