Thrombosis and Hemophilia: Little More Evidence, Much More Guidance.

Hermans, Cédric
(2023) HemaSphere — Vol. 7, n° 6, p. e918 [1-2] (2023)

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Abstract
The deficiency in factor VIII (FVIII) or factor IX (FIX) that characterizes hemophilia in theory provides physiological protection against thrombosis. Clinical experiences, numerous publications, and several registries indicate the opposite. Thrombosis is not uncommon among patients with hemophilia (PWH), although those with severe or moderate forms are less affected. These thrombotic events are becoming more frequent, causing increasing concern and management difficulties. [...]
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Hermans, C. (2023). Thrombosis and Hemophilia: Little More Evidence, Much More Guidance. HemaSphere, 7(6), e918 [1-2]. https://doi.org/10.1097/HS9.0000000000000918 (Original work published 2023)