Use of dexmedetomidine for pain control

(2010) F1000 medicine reports [electronic resource] — Vol. 2, p. 1-4 (2010)

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Abstract
For many years, clonidine, an α2-adrenergic receptor (α2-AR) agonist, has been widely used as an analgesic adjuvant in perioperative conditions and pain therapy. Dexmedetomidine (DMET) is currently the most potent α2-AR agonist available and was first approved as a sedative agent for use in the intensive care unit. However, DMET has recently been investigated for its analgesic effects and has the potential to become an alternative to clonidine.
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Grosu, I., & Lavand’homme, P. (2010). Use of dexmedetomidine for pain control. F1000 medicine reports [electronic resource], 2, 1-4. https://doi.org/10.3410/M2-90 (Original work published 2010)