The clinical relevance of ferritin concentration in the cerebrospinal fluid.

Sindic, Christian;Collet-Cassart, D;Cambiaso, Cesar;Masson, Pierre;Laterre, Emile-Christian
(1981) Journal of Neurology, Neurosurgery and Psychiatry — Vol. 44, n° 4, p. 329-333 (1981)

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Authors
  • Sindic, ChristianUCLouvain
    Author
  • Collet-Cassart, D
    Author
  • Cambiaso, CesarUCLouvain
    Author
  • Masson, PierreUCLouvain
    Author
  • Laterre, Emile-ChristianUCLouvain
    Author
Abstract
By means of a new technique (Particle Counting Immunoassay), we have determined the level of ferritin in 470 samples of cerebrospinal fluid of patients with various neurological disorders. The median value obtained in a control group was 2.3 ng/ml with an upper limit at 5.5 ng/ml. the concentrations in the serum and cerebrospinal fluid were independent, but that in cerebrospinal fluid correlated with its total protein content. High values of ferritin were found in infectious meningo-encephalitis, in vascular diseases of the central nervous system, and, unexpectedly, in several cases of dementia without obvious vascular pathology.
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Citations

Sindic, C., Collet-Cassart, D., Cambiaso, C., Masson, P., & Laterre, E.-C. (1981). The clinical relevance of ferritin concentration in the cerebrospinal fluid. Journal of Neurology, Neurosurgery and Psychiatry, 44(4), 329-333. https://hdl.handle.net/2078.5/35914 (Original work published 1981)