Proton therapy PBS plan real-time simulation and visualisation tool

Dasnoy-Sumell, Damien
(2017) ULB-Cancer Research Center — Location: Campus Erasme, Bruxelles (22.September.2017)

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  • Dasnoy-Sumell, DamienUCLouvain
    Author
Abstract
One of the possible next steps of improvement in proton therapy and radiotherapy in general is the use of real-time imaging during treatment. Recently, hybrid imaging-treatment solution have been developed for standard radiotherapy, such as the MR-Linac technology which was first used for online replanning. With such devices, we can expect in the future inter-fraction uses of continuous imaging or even intra-fraction real-time applications. A similar solution is not yet available for protons, mainly because the hardware challenges of building such a machine are more difficult to overcome. But, the possible gain in treatment quality of this kind of hybrid machine is expected to be even higher with protons than with photons, due to the difference in dose deposition profiles and the motion impact on dose distribution. MRI is probably the best choice of modality for such a continuous imaging application, due to its non-irradiant effect, and for its soft tissue contrast performances. In this context, we developed a tool to visualize and evaluate in real-time proton therapy Pencil Beam Scanning (PBS) treatment plans on dynamic images. This will allow us to compare different treatment strategies, using or not the simultaneous imaging and treatment possibility, and estimate the gain in treatment quality that could be expected from a PBS-MRI hybrid machine.
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Citations

Dasnoy-Sumell, D. (2017). Proton therapy PBS plan real-time simulation and visualisation tool. ULB-Cancer Research Center, Campus Erasme, Bruxelles. https://hdl.handle.net/2078.5/269297