Taken together, the data suggest the miRNA34s might be key effectors of p53 tumor-suppressor function, and their inactivation might contribute to certain cancers.
Bommer, G., Gerin, I., Feng, Y., Kaczorowski, A. J., Kuick, R., Love, R. E., Zhai, Y., Giordano, T. J., Qin, Z. S., Moore, B. B., MacDougald, O. A., Cho, K. R., & Fearon, E. R. (2007). p53-mediated activation of miRNA34 candidate tumor-suppressor genes. Current biology : CB, 17(15), 1298-1307. https://doi.org/10.1016/j.cub.2007.06.068 (Original work published 2007)