High doses of bromocriptine used for treatment of Parkinson's disease may be associated with pleuropulmonary complications. Isolated pleural effusions are a rare manifestation as is lower limbs edema are an exceptionally one. We report the case of a 67-year-old man, treated since five years by a daily dose of 30 mg of bromocriptine for Parkinson's disease, who developed important leg's edema and a few months later an exsudative right pleural effusion. No etiologies were found. Bromocriptine,vas discontinued. The evolution was characterized by nearly complete resolution of pleural effusion and disparition of lower limbs edema.
Messiaen, T., Lefebvre, C., Weynand, B., & Pieters, T. (1996). [Epanchement pleural et importants œdèmes des membres inférieurs induits par la bromocriptine]. La Revue de médecine interne, 17(8), 680-683. https://doi.org/10.1016/0248-8663(96)87156-6 (Original work published 1996)